Incidence and Geographic Distribution of Gastroenteropancreatic (GEP) Neuroendocrine Tumors (NETs): A Systematic Review of the Literature

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Introduction: Based on the literature, the world-wide incidence of neuroendocrine tumors (NETs) seems to be increasing, however, a systematic literature overview is lacking.

Aim(s): To collect all data available on the incidence and population characteristics of GEP NETs in order to establish their epidemiology.

Materials and methods: A sensitive MEDLINE search was performed. The papers were selected via a cascade process which restricted the initial pool of 7,991 articles to 31 using predefined in- and exclusion criteria. Original articles evaluating the incidence of sporadic GEP NETs in regional, institutional and national registries were considered.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Fraenkel M

Authors: Fraenkel M, Kim M, Faggiano A, De Herder W, Valk G,

Keywords: neuroendocrine tumor, epidemiology, incidence,