ENETS studies

Project title: "Development of a multiplex immunohistochemistry panel to predict relapse free survival and treatment response on biopsy specimen of pulmonary carcinoid tumours"

Specific aims:

• Diagnosis of a patient suffering from lung carcinoid (NET gr I-II) using a biopsy specimen is imprecise, potentially affecting choice of surgery and systemic treatment
• New techniques are required that enable clinicians to improve diagnostic separation and prediction of disease recurrence
• Using multiplex immunohistochemistry techniques we will establish a prediction model combining recent findings on protein expression related to prognosis and gene expression profiles separating carcinoid subtypes
• Using this panel we aim to improve clinical outcome of patients suffering from lung carcinoid

Principle investigator: Maastricht University Medical Centre, Jules Derks

This project is supported through an ENETS Translational Medicine Fellowship.