Introduction: Insulinoma, a pancreatic ß-cell tumor, comprises 55% of neuroendocrine tumors with an annual incidence of 3-10/million. 10% are malignant, 10% are multiple and half of them present in MEN-1.
Aim(s): Presentation of four newly diagnosed insulinoma patients aged 18-60, within an eight-month interval.
Materials and methods: All patients presented with mild neuroglycopenic symptoms at least two years before the diagnosis. Whipple’s triad, insulin glucose ratio>0.4, c-peptide>2.5ng/ml during hypoglycemia provided the biochemical diagnosis. Chromogranin A determination and CT and/or MRI scan of the abdomen were performed in all patients.
Conference: 8th Annual ENETS Conference (2011)
Presenting Author: Dr Vasiliki Daraki
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