Intra-Operative Portal Vein Insulin Assay Combined with Occlusion of the Pancreas for Complicated Pancreatogenous Hypoglycemia

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Introduction: Pancreatogenous hypoglycemia is a rare endocrine disorder. The precise localization of hypersecreting tissue and determination of complete resection are two main challenges for complicated pancreatogenous hypoglycemia, such as multiple endocrine neoplasia syndromes type-1 (MEN-1) and nesidioblastosis.

Aim(s): To assess the significance of intraoperative portal vein insulin assay for complicated pancreatogenous hypoglycemia.

Materials and methods: Two patients with Whipple's triad syndrome were diagnosed with MEN-1 and nesidioblastosis, respectively. Rapid portal vein insulin assay combined with temporary occlusion of the pancreas were applied in both patients.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: yang z

Authors: Yang Z, Tan H, Sun Y, Si S, Xu L,

Keywords: insulin assay, pancreatogenous hypoglycemia, nesidioblastosis, MEN1, portal vein,