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Is Octreotide Benefitial in Patients with Metastatic Gastroenteropancreatic (GEP) and Hepatobiliary Neuroendocrine Carcinoma (NEC)?

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Introduction: Neuroendocrine carcinomas (NECs) of the gastroenteropancreatic (GEP) and hepatobiliary (HB) tract are rare and a heterogenous group of malignancies. Octreotide showed the anti-tumor activity in well-differentiated metastatic midgut neuroendocrine tumors (NETs).

Aim(s): It has not been evaluated whether octreotide in NEC affects survival outcome or not.

Materials and methods: We analyzed 17 patients (6 ; HB- and 11 ; GEP- tract) with metastatic NEC who had been diagnosed between January 2009 and June 2012. All patients had one or more cytotoxic chemotherapy and nin had received octreotide as a single agent (n=3) or combination of cytotoxic chemotherapy (n=6) during treatment period.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Kim S,

Keywords: NEC, octreotide, GEP, HB,

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