Lack of Accuracy of Circulating Chromogranin A in the Preoperative Diagnosis of Lung Neuroendocrine Tumors

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Introduction: While the role of the circulating neuroendocrine (NE) marker Chromogranin A (CgA) in the clinical management of GEP NET has been extensively discussed, the same role in thoracic NE tumors (TNET) remains to be better clarified.

Aim(s): To establish the diagnostic accuracy of CgA in the preoperative diagnosis of the NE differentiation of a nodular lesion suspect for being a TNET.

Materials and methods: The study was performed among 2,461 patients in which CgA was evaluated (CIS-Bio, normal range 19,4-98,1 ng/ml ) in 654 suspected pulmonary nodules.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Scarpelli G, Daddi N, Maiettini D, Pascucci C, Minotti V,

Keywords: carcinoid, Chromogranin, diagnosis ,