Large Cell Neuroendocrine Carcinoma of the Lung with Atypical Evolution and Great Response to Innovative Treatments

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Introduction: Pulmonary neuroendocrine tumors are a group of heterogeneous neoplasms that represent 1% to 2% of all lung cancers.

Aim(s): Case

Materials and methods: A 58yo man went to the Pneumology service for a 1-month evolution productive cough accompanied by hemoptoic sputum and weight loss of approximately 4Kg. in the last 2 months. We realized chest radiography is performed, in which observed a density increase, suggestive of pulmonary nodule, which is confirmed immediately by CT.It was discussed in committee and it was decided to perform right superior lobectomy;The pathology was positive for NEURONDOCRINE CARCINOMA OF LARGE CELLS,2.8cm with mitotic 14 and Ki67>20%,N0.We started adjuvant chemotherapy with Cisplatin/Vinorelbine 4 cycles. In October/09,showed bones recurrence and multiple liver metastases.Treatment with with Cisplatin / Etoposide is offered, progressing after 4 months.It is decided to perform an Octreoscan,being positive.We proposed treatment with Somatostatin analogues.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Escala Cornejo R

Authors: Escala Cornejo R, Navarro M, García-Talavera SanMiguel P, Pérez López B, García Muñoz M,

Keywords: LCNEC,