Long-term Follow up of Peptide Receptor Radionuclide Therapy with 177Lu-dotatate in Advanced Well-differentiated Pancreatic Neuroendocrine Tumors Abstract #1277

Introduction: 177Lu-dotatate(Lu-PRRT) is a valid therapeutic option in advanced G1-G2 pancreatic neuroendocrine tumors (P-NETs)
Aim(s): We evaluated long-term efficacy and toxicity in 65 consecutive patients (pts) with P-NETs treated with a personalized activity of Lu-PRRT. We also evaluated the role of FDG PET as an independent prognostic factor in P-NET pts
Materials and methods: 65 consecutive pts with P-NETs were enrolled in a prospective study. Pts were treated with two different total activities (18.5GBq or 27.8 GBq) in 5 cycles on the basis of kidney function and bone marrow parameters. 59 pts underwent FDG PET before Lu-PRRT
Conference: 13th Annual ENETS conference (2016)
Category: PRRT-Ablative therapies-Endoscopic treatment
Presenting Author: MD Maddalena Sansovini
Keywords: PRRT, FDG-PET, P-NET

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