Long-term Follow-up of Tissue Valve Prostheses in Carcinoid Heart Disease
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Introduction: Development of carcinoid heart disease (CHD) increases morbidity and mortality. Cardiac valve replacement surgery improves functional class, but tissue prosthesis degeneration can occur early in CHD.
Aim(s): A retrospective study of a case series of tissue valve prostheses in CHD was performed to determine the prevalence, nature and rate of degeneration.
Materials and methods: Twenty-two CHD patients from our institution underwent cardiac valve replacement over 32 months. Cardiac mortality was 23% at two years. Median echo follow-up was 24 months for 11 patients who survived over six months postoperatively. CHD-related tissue prosthesis degeneration was defined as progressive leaflet thickening with regurgitation and/or stenosis.
Conference: 8th Annual ENETSConcerence (2011)
Presenting Author:
Authors: Knight D, Bhattacharyya S, Toumpanakis C, Caplin M, Davar J,
Keywords: carcinoid heart disease, bioprosthetic valves, 5-HIAA, chromogranin A, pulmonary homograft stenosis,
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