Long-Term Haematological and Renal Toxicity of 90Yttrium-DOTA-Octreotate in the Treatment of Advanced Neuroendocrine Tumors(NETs) Abstract #768

Introduction: Peptide receptor radiation therapy (PRRT) is an established treatment for advanced NETs. Renal/haematological toxicity are recognised adverse effects.
Aim(s): To assess the long-term toxicity of PRRT with Yttrium90-tyr3-DOTA-octreotate in progressive NETs.
Materials and methods: Two-hundred and thirty-five patients receiving 2.9-3.3 GBq/treatment cycle (with prophylactic aminoacid infusion) were included. Weekly serology was performed for eight weeks post cycle. Median 24 month follow-up results were analysed. Bone marrow (BMT) and renal (RT) toxicity patients were grouped according to severity: A (WHO grade 1-2) and B (grade 3-4).
Conference: 10th Annual ENETS Conference 2013 (2013)
Category: PRRT-Ablative therapies-Endoscopic treatment
Presenting Author: DR VINCENT Cheung

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