Midkine is a New Novel Serum Biomarker in Small Intestinal Neuroendocrine Tumors (SI-NETs). Abstract #1278

Introduction: SI-NETs are often diagnosed late, which limits curative treatment options.
Aim(s): Our aim was to identify new novel biomarkers in SI-NETs, in order to enable early diagnosis, prognostication and monitoring of treatment response.
Materials and methods: Ninety-two biomarkers were screened in blood serum from 67 patients with SI-NETs and 23 age-matched healthy controls using multiplex proximity ligation assay (PLA). Confirmation of findings by multiplex PLA was performed by immunohistochemistry (IHC) on tumors, followed by ELISA assays in blood serum.
Conference: 13th Annual ENETS conference (2016)
Category: Biomarkers
Presenting Author: Kosmas Daskalakis
Keywords: Biomarker, SI-NET

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