Pancreatic Neuroendocrine Tumors Associated with Mesenchimal Neoplasms of the GI Tract Abstract #525

Introduction: Neuroendocrine pancreatic tumors (NPT) are occasionally associated with mesenchimal tumors in neurofibromatosis type 1 but rarely in sporadic cases. We report five cases of NPT associated with other rare mesenchimal neoplasms of the GI tract, observed in our Department from 2003 to 2011.
Aim(s): To evaluate clinical outcome in patients with NPT associated with a rare mesenchimal neoplasm.
Materials and methods: All five patients (3M/2F, averaging 67 years) had preoperative diagnosis of NPT. They all underwent surgical resection: one middle pancreatectomy, two left pancreatectomy and two pancreaticoduodenectomy. The following associations were observed: one benign insulinoma with a jejeunal leiomyoma, two nonfunctioning NPT with a gastric GIST and two duodenal GISTs respectively, one non functioning metastatic NPT with a cecal GIST, one malignant metastatic gastrinoma with one jejunal and two duodenal GISTs. In all cases, the mesenchimal lesions were low-risk neoplasms.
Conference: 9th Annual ENETS Conference (2012)
Category: Clinical
Presenting Author: Prof. Claudio Pasquali

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