Pancreatic Neuroendocrine Tumors: Experience of Endocrinology Department of the University Hospital of Coimbra

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Introduction: Pancreatic neuroendocrine tumors (PNETs) are uncommon neoplasms, comprising 1-2% of all pancreatic tumors. The majority are nonfunctional. Of the functional tumors, insulinomas are the most common.

Aim(s): To analyze retrospectively the clinical files of patients with PNETs followed in the department of endocrinology at the University Hospital of Coimbra.

Materials and methods: Nineteen patients (10M;9F), mean age 50.4±20.4 years, were studied. The clinical, biochemical, imaging, pathological, treatment and follow-up data of 14 insulinomas and 5 nonfunctional PNETs were collected. Seven patients had hereditary tumors: four were already diagnosed as MEN-1; one had VHL disease; and two, father and daughter, insulinoma.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Vieira A, Santos J, Gomes L, Moreira A, Alves M,

Keywords: pancreatic neuroendocrine tumors, insulinoma, hereditary tumor syndromes,