PD-L1 Expression is Associated with Grade of Neuroendocrine Tumors Abstract #1290

Introduction: Neuroendocrine neoplasms are divided into well-differentiated neuroendocrine tumors (WDNETs) and poorly differentiated neuroendocrine carcinomas (PDNECs).The correlation between Gastroenteropancreatic Neuroendocrine Neoplasms (GEPNENs) and immunocheck point molecule-PD-L1 is still unclear now.
Aim(s): This study want to explore the relationship between PD-L1 expression and clinical-pathological parameters of GEPNENs.
Materials and methods: Totally 59 GEPNENS patients who received surgery were involved in this study. The patients included 21 cases from stomach (4 WDNETs and 17 PDNECs), 2 cases from duodenum (2 PDNECs), 8 cases from colon (8 PDNECs), 4 cases from rectum (4 PDNECs), and 24 cases from pancreas (10 WDNETs and 14 PDNECs).PD-L1 expression was detected by Immunohistochemistry on Tissue Microarray(TMA) of these cases.
Conference: 13th Annual ENETS conference (2016)
Category: Pathology, grading, staging
Presenting Author: Professor Zhongwu Li

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