Peptide Receptor Radionuclide Therapy (PRRNT) in Patients with Metastasized Neuroendocrine Tumor Having Single or Non-functional Kidney - Is it Safe? Abstract #238

Introduction: Nephrotoxicity is one of the primary concerns in PRRNT of metastasized neuroendocrine tumors (NET).
Aim(s): To determine if PRRNT can be performed in patients (pts) with only one kidney or non-functional kidney(s) and progressive, life-threatening NET.
Materials and methods: Twenty-five patients (mean age 57 yr±13) with metastasized NET and having a single kidney (n=19), functional single kidney (n=4), or on dialysis (n=2) were treated with Y-90 (n=2) , Lu-177 (n=21) DOTATATE and combination of Lu-177 and Y-90 (n=2) under renal protection using amino acids (lysine+arginine) and in addition a gelatine agent (Gelofusal).
Conference: 8th Annual ENETS Conference (2011)
Category: Clinical
Presenting Author: Dr. Vikas Prasad

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