pNET G3 Tumor Stabilization Achieved by an Individualized Molecular Therapy Based on Tumor Genome Sequencing Results

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Introduction: High-grade pancreatic neuroendocrine neoplasms (pNENs) constitute a heterogeneous group of malignant neoplasms, encompassing neuroendocrine tumors (NET) G3 and carcinomas (NEC). Due to poor data on NET G3 tumors no standard therapy in metastatic disease could be established so far. Tumor genome sequencing might help to better profile NET G3 tumors and could provide novel opportunities for individualized and thereby successful patient specific treatments.

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Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Steurer M

Authors: Steurer M, Lauer U, Hinterleitner C, Sipos B, la Fougère C,

Keywords: NET G3, tumor genome sequencing, individual therapy,