Potential Anti-Tumor Activity of Biguanides and Statins in Neuroendocrine Tumor Cells

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Introduction: Recent studies have suggested that biguanides and statins have beneficial effects on various cancer types; however, the precise effects and the molecular mechanisms underlying this pathophysiological association are still not well understood in neuroendocrine tumor (NETs).

Aim(s): To investigate the potential effects of different biguanides and statins on NETs.

Materials and methods: Proliferation, migration, secretion and gene expression in BON1/QGP1 cells.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Herrera-Martínez A, Pedraza-Arévalo S, López-López F, Gahete M, Gálvez-Moreno M,

Keywords: NETs,biguanides,statins,