Primary Hepatic Neuroendocrine Carcinoma: Case Report and Literature Review

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Introduction: Primary hepatic neuroendocrine carcinoma (PHNEC) is an extremely rare neuroendocrine carcinoma (NEC) that originate from the liver. The diagnosis of PHNEC remains challenging because of its rarity, and its lack of unique clinical features. Available treatment options for PHNEC include surgical resection of the liver tumor(s), radiotherapy, liver transplant, transcatheter arterial chemoembolization (TACE), and administration of somatostatin analogues.

Aim(s): To report a PHNEC case and discuss the diagnosis and therapeutic options.

Materials and methods: A 30-year-old-male with history of pT1a papillary thyroid carcinoma treated three months ago with surgery and radioiodine therapy, was admitted in our department in August 2019, presenting with upper abdominal pain for over 2 months.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Saidi M, Ghomari S,

Keywords: primary hepatic neuroendocrine carcinoma, liver biopsy, immunohistochemical staining, Somatostatin analogue,