Primary Lymph Node Gastrinoma or Metastatic Gastrinoma with Unidentified Primary Tumor Site? Abstract #690

Introduction: The existence of primary lymph node gastrinoma remains controversial.
Aim(s): Investigation of a lymph node containing a gastrinoma with an unidentified primary tumor.
Materials and methods: We report on a male aged 42 presenting in 1999 with nausea, vomiting and reflux symptoms (1). ZES was diagnosed but no tumor was identified and PPI treatment did not improve symptoms. Fasting plasma gastrin and basal gastric acid production was elevated but chromogranin A was normal. EUS showed a thickened duodenal wall. On repeated EUS in 2010 a 5x8 mm prepyloric mass was revealed which was positive on 68 Ga DOTATATE PET/CT and confirmed on angiography. Chromogranin A was elevated (90 pmol/l) and fasting plasma gastrin further elevated (290 pmol/l).
Conference: 10th Annual ENETS Conference (2013)
Category: Epidemiology/Natural history/Prognosis - Descriptive epidemiology
Presenting Author: Helen Miller

To read results and conclusion, please login ...

Further abstracts you may be interested in

#283 Primary Lymph Node Gastrinoma: A Genuine Entity? Two Case Reports and a Review of the Literature
Introduction: The existence of primary lymph node gastrinoma has been proposed but is controversial. We report two cases (Case A - 37-year-old male, Case B - 43-year-old male) of apparent primary lymph node gastrinoma.
Conference: 8th Annual ENETS Conference (2011)
Category: Clinical
Presenting Author: Dr Richard W Carroll
#2007 The Exact Prognostic Significance of Lymphatic Metastasis of Jejunoileal Neuroendocrine Tumors
Introduction: How to evaluate the prognostic significance of lymphatic metastasis in patients with jejunoileal neuroendocrine tumors (jNETs) is still not conclusive.
Conference: 15th Annual ENETS conference (2018)
Category: Epidemiology/Natural history/Prognosis- Registries, nationwide and regional surveys
Presenting Author: Professor Jie Chen
Authors: Zhang Y, Chen L, Song Y, Chen M, ...
#135 The importance of endoscopic ultrasound in detecting recurrent gastrinoma in a case of MEN 1
Introduction: Approximately 25-30% of patients have gastrinomas as part of the inherited syndrome Multiple Endocrine Neoplasia 1 (MEN 1). Gastrinomas occur in the pancreas, duodenum or peripancreatic lymph nodes. Diagnosis is made by clinical history, gastroscopy, and measurement of serum gastrin, gastric juice pH, CT scan, endoscopic ultrasound (EUS) and somatostatin receptor scintigraphy (SRS). Localization of gastrinomas in patients with MEN 1 is challenging due to their small size, frequent duodenal location, and multiplicity.
Conference: 7th Annual ENETS Conference (2010)
Category: Clinical
Presenting Author: Prof. Laura De Marinis
#353 Pattern and Clinical Predictors of Lymph Node Involvement in Neuroendocrine Neoplasms of the Pancreas
Introduction: Pancreatic neuroendocrine neoplasms (PNENs) are often indolent without pathological lymph node metastasis (pN1). Therefore, in patients with low risk of pN1, a lymphadenectomy could be avoided.
Conference:
Category: Basic
Presenting Author: Stefano Partelli
#349 Gastrointestinal Stromal Tumor (GIST) Of The Esophagus In A Patient With MEN-1 And-Related Pancreatic Gastrinoma
Introduction: Both Multiple Endocrine Neoplasia type 1 (MEN-1; OMIM #613733)-related-gastrinomas and Gastrointestinal Stromal Tumors (GISTs; OMIM #606764) are rare neoplasms and their association has been rarely reported so far.
Conference:
Category: Basic
Presenting Author: Dr Roberta E Rossi