Prognosis of Stage IV Sporadic Pancreatic Neuroendocrine Tumors (pNET): Tumor Slope is Prognostic Together with Tumor Burden and Grade Abstract #1452

Introduction: Currently, no prognostic stratification exists in stage IV pNET patients.
Aim(s): To provide prognostic stratification of stage IV pNETs by analyzing 1)prognostic parameters at the time of stage IV diagnosis 2)Per RECIST tumor slope over 3-6 months prior therapy.
Materials and methods: Multicenter retrospective study. Inclusion criteria were: 1)Confirmed pNET naive of therapy 2)Measurable stage IV disease 3)sporadic tumor. Primary endpoint was OS. Two multivariate analyses were performed: model 1 “at the time of stage IV diagnosis”; model 2 "after the characterization of tumor slope".
Conference: 13th Annual ENETS conference (2016)
Category: Epidemiology/Natural history/Prognosis - Prognosis
Presenting Author: Medical Doctor Vincenzo Marotta

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