Introduction: Neuroendocrine (NE) malignant neoplasms commonly metastasize to the liver, which can be the only site of metastatic disease. The clinical course of patients who undergo surgical resection of hepatic NE metastases varies widely and the reported factors affecting survival have not been identified.
Aim(s): To compare the weight of prognostic factors (PF) after liver resection for metastatic NE and non-NE colorectal cancers.
Materials and methods: Nine patients with NE tumors (cases) and 15 age- and sex-matched patients with non-NE colorectal cancer (controls) developed hepatic metastases during follow-up. The following parameters have been considered: age (>50 v. ≤50 years), main size of the metastases (>5 v. ≤5 cm), histologic grade (G1 v. G2-3), margin status (microscopically negative=R0 vs. R1), extrahepatic disease (ED). Odds ratio (OR) estimates, associated 95% confidence interval (95% CI), and the relative p-value were obtained.
Conference: 10th Annual ENETS Conference 2013 (2013)
Category: Epidemiology/Natural history/Prognosis - Prognosis
Presenting Author: Professor Franco Lumachi
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