Prognostic Relevance of Pancreatic Neuroendocrine Tumors Grading on EUS-FNA Abstract #1609

Introduction: Since WHO 2010, resected pNETs are graded as G1, G2 or G3 using the Ki67-LI. EUS-FNA is often used for diagnosis but few studies have assessed its value for grading.
Aim(s): To compare Ki67-LI obtained on cytology (cG) with histology (hG). To assess: - the influence of tumour size, and number of counted cells on FNA grading - the overall survival (OS) and progression free survival (PFS)of patients based on cG
Materials and methods: EUS-FNA was performed for 102 pNETs (57 resected), retrospectively included in this multicentre study. cG (200 cells counted) was done on all FNAs. For 29 FNAs, > 2000 cells were counted (14 resected). Comparison was made between hG and cG for the 57 resected patients. Patients were followed-up until 06/2016.
Conference: 14th Annual ENETS conference (2017)
Category: Pathology, grading, staging
Presenting Author: Prof. Dr. Ivan Borbath
Keywords: EUS-FNA, KI67, pNET, OS

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