Prognostic Value of Immunohistochemical Expression of Somatostatin Receptors (SS-R2 and SS-R5) in the Gastroenteropancreatic Neuroendocrine Tumors, Diagnosed in the University Hospital of Pleven, Bulgaria, from the Period 2010 to November 2017

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Introduction: Sоmatostatin is a regulatory peptide with a variety of actions in normal and tumor cells. In recent years there are a lot of observations suggesting that the gastrointestinal neuroendocrine tumors (GEP-NETs) expressed somatostatin receptors (SS-R).The expression could be valuable for the prognosis of patients with GEP-NETs due to the research evidence that well-differentiated tumors express SS-R in the great majority of the cases.

Aim(s): Our idea is to check this correlation.

Materials and methods: This is an initially retrospective study about the immunohistochemical expression of SS-R2 and SS-R5 in the gastroenteropancreatic neuroendocrine tumors diagnosed in the University Hospital of Pleven, Bulgaria from the period 2010 to November 2017.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Vladova P

Authors: Vladova P, Iliev S, Popovska S,

Keywords: gastroenteropancreatic neuroendocrine tumors, SS-R, prognostic value,