Pulmonary Function Test Physiology and Progression in Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia Abstract #2002

Introduction: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare condition characterised by a generalised proliferation of pulmonary neuroendocrine cells within the respiratory epithelium. Little is known of its affects on pulmonary function both at the time of diagnosis and prospectively.
Aim(s): To characterise baseline pulmonary function and define the change in pulmonary function over time in patients with DIPNECH.
Materials and methods: Retrospective analysis of pulmonary function data for patients with a histological diagnosis of DIPNECH was performed. At baseline, pulmonary function was characterised as: obstructive, small airways obstruction, restrictive, mixed or normal. FEV1 was the main measure of pulmonary function, and simple linear regressions were created for patients with longitudinal data. This allowed basic statistical analysis of the change in FEV1 compared to the predicted change.
Conference: 15th Annual ENETS conference (2018)
Category: Non digestive NETs (bronchial, thymic, others) - diagnosis and therapy
Presenting Author: Joseph Barlow

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