Radioembolization with 90Y-Labelled Resin Microspheres in Patients with Liver Metastases from Neuroendocrine Tumors

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Introduction: Hepatic arterial embolization with 90Y-labelled microspheres is a method of delivering radioactivity to liver tumors, that has been used to treat primary hepatocellular carcinomas and liver metastases from colorectal carcinomas and neuroendocrine tumors.

Aim(s): To evaluate the efficacy and safety of radioembolization in patients with neuroendocrine tumors.

Materials and methods: 38 patients with progressing neuroendocrine liver metastases underwent 51 embolizations with 90Y-labelled resin microspheres (SIR-Spheres®). 31 embolizations were performed in the right, 11 in the left and 9 in both liver lobes. Mean activity was 1.3 GBq. Evaluation was performed with CT or MRI according to modified RECIST criteria.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Granberg D

Authors: Ebeling-Barbier C, Garske-Roman U, Antonodimitrakis P, Sandström M, Nyman R,

Keywords: radioembolization, neuroendocrine, liver metastases,