Introduction: Patients (pts) with metastatic or locally advanced, non-resectable, grade 1 or 2 Well-differentiated duodeno-pancreatic (WDDP) NETs are treated following European guidelines. Pts with aggressive disease, i.e. progressive and/or symptomatic metastases and/or with significant hepatic invasion (> 30-50%), and/or bone metastases, anti-tumour therapy should receive systemic combination of chemotherapy once disease control is obtained.
Aim(s): The aim is to stop chemotherapy until progression. REMINET is an academic randomized, double-blind, placebo-controlled, phase II/III study designed to evaluate whether lanreotide (LAN) as maintenance treatment after L1 therapy.
Materials and methods: Main eligibility criteria: Adults pts with a metastatic (synchronous or metachronous) or locally advanced, non-resectable, grade 1 or 2 WDDP NETs and documented control disease after L1 therapy at least 4 weeks prior to randomization.
Conference: 14th Annual ENETS conference (2017)
Category: Medical treatment – Chemotherapy, medical treatment - others
Presenting Author: Côme Lepage
Authors: Lepage C
, Dahan L
, Legoux J L
, Le Malicot K
, Guimbaud R
, Tougeron D
, Lièvre A
, Bouarioua N
, Petorin C
, Pavel M
, Borbath I
, Toumpanakis C
, Smith D
, Ducreux M
, Walter T
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