Results from a Phase 2, Open-Label, Multicenter, Randomized Study of the Novel, Octreotide (Oct) Subcutaneous (SC) Depot Formulation in Patients with Functioning Neuroendocrine Tumors (NETs) and Acromegaly Previously Treated with Long-Acting Octreotide

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Introduction: Oct sc depot is a novel, ready to use formulation administered via a thin needle.

Aim(s): To characterize the PK profile and to assess the efficacy, safety and tolerability of oct sc depot vs long-acting oct.

Materials and methods: Adult pts with functioning NETs or acromegaly treated for ≥2 months with long-acting oct (10/20/30mg every four weeks [q4w]) received the last dose of long-acting oct in period 0 (P0) and were randomized 28 days later to receive oct sc depot 10mg every two weeks (q2w) or 20mg q4w for 3 months (period 1 [P1]).

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Pavel M, Borson-Chazot , Hörsch D, Lahner , Pivonello R,

Keywords: octreotide sc depot, NET,

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