Risk Stratification Using Octreotide Test For Patients With Gastro-Entero-Pancreatic Neuroendocrine Tumors: Results Of Prospective Validation Of The Test Abstract #354

Introduction: Criteria for treatment with somatostatin analogs (SSAs) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are presence of somatostatin receptors, a positive Octreoscan® or hormonal decrement >50% after octreotide s.c. injection (octreotide test, OT). We demonstrated that a plasma CgA decrement >/=30% after OT is a selection criterion able to predict the clinical response to SSAs.
Aim(s): We evaluated OT prognostic value in a prospective cohort of patients.
Materials and methods: From January 2008 to June 2010 we prospectively evaluated 44 GEP-NET patients, undergoing OT with plasma CgA determination at 0, 3, 6 hours. SSAs were given by monitoring clinical outcome.
Conference:
Category: Basic
Presenting Author: Dr Roberta Elisa Rossi

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