Screening of Differentially Expressed Genes in Gastric Neuroendocrine Neoplasms Based on Human Transcriptome Array

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Introduction: Gastric neuroendocrine neoplasms (g-NENs) are a heterogeneous group of tumors.

Aim(s): We tried to explore its underlying pathogenesis based on transcriptome array.

Materials and methods: We utilized Human Transcriptome Array 2.0 to screen the differentially expressed genes (DEGs) in g-NENs by using three g-NEN tissues and adjacent normal gastric tissues. The gene ontology (GO) analysis, including biological process, molecular function and cellular component analysis, was performed to uncover the biological functions of DEGs. The kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analysis was used to find out the related signal pathways.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Wei Y, Bai J, He N, Hua X, Tang Q,

Keywords: g-nen, human transcriptome array, differentially expressed genes, extracellular matrix,