Serum chromogranin A as tumor marker in neuroendocrine tumors

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Introduction: Serum chromogranin A (CgA) is used as a tumor marker for neuroendocrine tumors (NETs).

Aim(s): Assessment of the sensitivity of the tumor marker CgA in NETs of the gastroenteropancreatic system.

Materials and methods: CgA levels were measured in serum samples from 110 patients with midgut and pancreatic NETs (n=62 and n=48, respectively) in a retrospective single-center series during clinical routine in the years 2000 – 2009. For CgA determination, a commercially available immunoradiometric assay (IRMA, CIS-Bio) was used (""cutoff"" < 98 ng/ml).

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Nölting S, Kuttner A, Lauseker M, Vogeser M, Haug A,

Keywords: neuroendocrine tumors, sensitivity, chromogranin A, liver metastases, CIS-Bio assay,