Signs of Carcinoid Heart Disease on Staging CT: Which Predictors are Helpful?

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Introduction: In patients with functionally active neueroendocrine neoplasms (NEN) carcinoid heart disease presenting primarily with tricuspid valve regurgitation (TR) is associated with high morbidity and mortality. Early diagnosis is crucial to improve prognosis.

Aim(s): To evaluate signs on CT imaging performed for tumor staging as predictors of TR in patients with functionally active NEN.

Materials and methods: Patients with functionally active NEN and different grades of TR were identified. Two readers independently reviewed contrast-enhanced staging CT performed shortly before or after echocardiography. Logistic regression and receiver operating analyses were used to asses the predictive value of right ventricle to left ventricle ratio (RV/LV ratio), ventricular septal bowing, retrograde contrast filling of the hepatic veins during contrast injection, and time to aortal enhancement >100 HU during bolus tracking (TAE >100 HU) for TR.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Baur A

Authors: Baur A, Kunz F, Pschowski R, Röpke T, Pavel M,

Keywords: computed tomography, staging, carcinoid heart disease,