The Challenge of Differential Diagnosis of Solid Pancreatic Lesions in Von Hippel-Lindau. Case Report

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Introduction: Von Hippel-Lindau (VHL) is an hereditary syndrome, characterized by a predisposition to develop benign and malignant tumors. Pancreatic involvement is present in 35-70% of cases and include cystic (simple cyst, serous cystoadenoma, mucinous tumor or IPMN) and solid lesions (neuroendocrine neoplasm (NEN), metastatic mass or pancreatic adenocarcinoma). Finally, a solid-type serous cystoadenoma (SSCA) has been reported. Differential diagnosis of these lesions may be difficult.

Aim(s): To present a case of an unclear solid pancreatic lesion in a patient affected by VHL.

Materials and methods: In a 32-year-old VHL man a CT scan, performed for follow up of pheocromocytoma, detected a contrast-enhanced lesion of 16 mm in the uncinate process without necrosis or calcifications.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Zilli A

Authors: Zilli A, Cavalcoli F, Maddalena P, Conte D, Massironi S,

Keywords: solid pancreatic lesions, VHL,