The Clinical Significance of Elevated Serum Procalcitonin in Patients with Gastroenteropancreatic Neuroendocrine Neoplasms

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Introduction: Elevated serum procalcitonin (PCT) was reported in some patients with neuroendocrine neoplasms (NEN), but its clinical significance in gastroenteropancreatic NEN (GEP-NEN) was still unknown.

Aim(s): To investigate the association between serum PCT and clinicopathological features, and overall survival (OS) in GEP-NEN.

Materials and methods: 130 patients with GEP-NEN were included. Serum PCT levels higher than 1.5× the upper limit of normal (≥ 0.075 ng/ml) were defined as elevated. Logistic regression analysis was used to evaluate the association between PCT levels and clinicopathological features. Kaplan-Meier method and Cox regression were used to study the prognostic significance of serum PCT.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Chen L

Authors: Chen L, Zhang Y, Chen M, Chen J,

Keywords: procalcitonin, neuroendocrine neoplasms, tumor grade, survival,