The Evolution of Surgical Strategies for Pancreatic Neuroendocrine Tumors (Pan-NENs): Time-Trend and Outcome Analysis from 587 Consecutive Resections at a High-Volume Institution

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Introduction: Reflecting their rarity and heterogeneity, Pan-NENs represent a clinical dilemma and there is a scarcity of data regarding their long-term follow-up after resection.

Aim(s): The objective of the present analysis is two-fold: first, to define the evolution of time trends on the surgical approach to Pan-NENs; second, to perform a complete analysis of the predictors of oncologic outcome.

Materials and methods: From the Institutional Pan-NEN database, 587 resected cases from 1990 to 2015 were extracted. The time span was arbitrarily divided into three discrete clusters enabling a balanced comparison between patient groups. Analyses for predictors of recurrence and survival were performed, together with conditional survival analyses.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Marchegiani G

Authors: Marchegiani G, Landoni L, Pollini T, Miotto M, Cingarlini S,

Keywords: Pancreas, Pan-NENs, Surgery, NET,