The Neuroendocrine Tumor in Choroid: An Unusual Metastatic Location (Clinical Case Report) Abstract #907

Introduction: Neuroendocrine neoplasms are tumors of various location and symptoms. This case shows the unusual choroidal location of the metastatic NEN.
Aim(s): To get the detailed histological typing for making the diagnosis and the next decisions.
Materials and methods: A 55-year-old man underwent the ocular examination due to steamed vision (10/2003). Due to retinal detachment and choroidal tumor suspicion, he was indicated to eyeball enucleation (3/2004). Metastasis of the NEN of unknown primary was detected, chromogranin, synaptofysin and NSE positive. Gastrointestinal endoscopy and bronchoscopy were negative, octreoscan with two deposits in the right lung lobe and anterior mesogastrium. The resection was done (9/2004) with NET G1 histology. The patient was asymptomatic. Regular monitoring detected two metastases in the liver ultrasound (2/2008), CT negative. Their size progression (octreoscan and MRI 4/2010) led to surgical intervention (6/2010). Ki-67 factor 1-2% again. Two radiofrequency ablations were done (9/2010, 3/2011). Ultrasound and octreoscan (5/2012) detected new metastases. Surgical intervention wasn't done due to acute erysipelas of the leg and heavy sleep apnoea syndrome. The patient has been incorporated into the CRAD 001T2302 study with everolimus.
Conference: 11th Annual ENETS Conference 2014 (2014)
Category: Clinical cases/reports
Presenting Author: M.D. Jaroslava Barkmanova

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