The Prognostic Value of the Expression of Cytokeratin 7 and 19 in Lungs and Pancreas Neuroendocrine Tumors Abstract #1689

Introduction: The expression of cytokeratins (CK) 7,19 rarely occurs in the low grade neuroendocrine tumors (NET) of lung and pancreas. It is known that part of the low grade typical (TC) and atypical (ATС) carcinoids of lung and pancreas (pNET-G1,G2) can progress quickly and to metastasize. It is important to distinguish NET with a less differentiated cells immunophentype.
Aim(s): To examine of the expression of CK 7 and 19 in NET.
Materials and methods: The expression of CK7 and 19 was examined by immunohistochemistry method in to 339 NET: 49 TC, 32 ATC, 60 small-cell (SCC), 11 large cell neuroendocrine carcinomas of the lung (LCC); 78, 98 pNET-G1 and G2 (respectively), 11 pNEC-G3.
Conference: 14th Annual ENETS conference (2017)
Category: Pathology, grading, staging
Presenting Author: Iya A Voronkova

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