Introduction: Neoplastic tissue exhibits high glucose utilization, which can be imaged by 18F-Fluorodeoxyglucose-positron emission tomography (FDG-PET). Whether FDG-PET is useful for neuroendocrine (NE) tumors, however, is questionable, due to the slow growth rate often observed in these tumors.
Aim(s): To investigate the diagnostic and prognostic value of FDG-PET and to compare this with the cellular proliferation index in these often slow-growing tumors.
Materials and methods: Ninety-eight prospectively enrolled patients with NE tumors underwent FDG-PET imaging. The prognostic value of FDG uptake and proliferation index, as determined by immunohistochemical staining for Ki-67 was evaluated. In addition, the diagnostic sensitivity of FDG-PET was assessed and the imaging results were compared with the proliferation index.
Conference: 7th Annual ENETS Conference (2010)
Presenting Author: M.Sc. Tina Binderup
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