Tie-2 and Angiopoietin-2 Plasma Levels as New Diagnostic Markers for Patients with Neuroendocrine Tumors. Data from One Clinical Center

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Introduction: Data concerning circulating levels of the angiogenic factors in patients with neuroendocrine tumors (NET) still remain insufficient.

Aim(s): To measure plasma levels of selected angiogenic factors in NET patients in order to find new diagnostic and prognostic markers in these unpredictable and highly vascularized tumors.

Materials and methods: The levels of the following factors were assessed with ELISA in 36 NET patients and 16 controls: VEGF, angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2), Tie-2, endostatin, osteopontin (OPN) and chromogranin A (CgA).

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Melen-Mucha G, Niedziela A, Mucha S, Motylewska E, Lawnicka H,

Keywords: angiogenic factors, blood plasma, NET patients,