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Treatment of unresectable neuroendocrine liver tumors with Y-90 microsphere

#71

Introduction: The primary therapy of liver lesions of NET is surgery but it is most possible for all patients. Selective internal radiation therapy (SIRT) is a newly available method to treats liver metastases.

Aim(s): To determine the efficacy and safety of treatment of unresectable NET tumors with SIRT.

Materials and methods: Twelve patients with NET were included in the study (35-88 years old, seven female, five male). All patients had already taken several therapies. The liver lesions were clearly identified with dynamic CT and In-111 octreotide scans befor therapy. Their liver fuctions were normal and no shunt >10% to lung from liver was observed with Tc-99m MAA scan. All patients were given the first therapy to the right lobe and three patients to the left lobe and additionally in three months. Brehmsstrahlung images were taken immediately after therapy to exclude the shunt to the lungs and gastrointestinal system. Liver functions, In-111 octreotide scan and dynamic CT were performed six weeks after the 90 Y treatment.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Kucuk O

Authors: Kucuk O, Lacin S, Oz I, Bilgic S,

Keywords: 90Y, liver NETS, intra-arterial radionuclide treatment,

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