Treatment with Somatostatin Analogs of Recurrent Type I Gastric Carcinoid in Patients with Autoimmune Chronic Atrophic Gastritis

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Introduction: The treatment of type 1 gastric carcinoids (GC1) is still debated, in view of their usual benign behavior.

Aim(s): To evaluate the outcome of patients with recurrent GC1 treated with somatostatin analogs (SSA).

Materials and methods: From January 2000 to September 2013, among 111 patients with chronic autoimmune atrophic gastritis, 23 patients were diagnosed with GC1. After they had the GC endoscopically removed, they underwent regular clinical and endoscopic follow-up. Plasma chromogranin A (CgA) and gastrin levels were measured in all patients. Patients showing recurrent GC1 were treated with SSA until gastrin fell below 400 pg/mL and there was no endoscopic/histological evidence of GC1.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Zilli A

Authors: Massironi S, Zilli A, Rossi R, Fanetti I, Ciafardini C,

Keywords: gastric carcinoid, NEN,