Triple Tracer Imaging Approach for the Non-Invasive Assessment of Chemokine Receptor 4 Expression in Gastroenteropancreatic Neuroendocrine Tumors Abstract #1596

Introduction: The theranostic twins [68Ga]Pentixafor and [177Lu]Pentixather for chemokine-directed endoradiotherapy (ERT) were recently developed.
Aim(s): We aimed to evaluate feasibility of non-invasive CXCR4 PET/CT imaging using [68Ga]Pentixafor in comparison to 68Ga-DOTA-D-Phe-Tyr3-octreotide ([68Ga]DOTATOC) and 18F-fluorodeoxyglucose ([18F]FDG).
Materials and methods: 12 patients with histologically proven GEP-NET underwent [68Ga]DOTATOC, [18F]FDG and [68Ga]Pentixafor PET/CT. Scans were analyzed on a patient as well as on a lesion basis.
Conference: 14th Annual ENETS conference (2017)
Category: Imaging (radiology, nuclear medicine, endoscopy)
Presenting Author: Dr. Rudolf Werner

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