Tumor Size Correlates with Grading in Nonfunctioning Pancreatic Neuroendocrine Tumors and Is Not Age-Dependent

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Introduction: Tumor growth and Ki67 value increase are associated with aggressiveness in nonfunctioning pancreatic neuroendocrine tumours (NF-PanNET), but their natural history is largely unknown. It is unknown if the evolution of NF-PanNET is time-dependant.

Aim(s): The aim is to evaluate a possible correlation between age, tumor size and grading in patients with NF-PanNET and its impact on disease free survival (DFS).

Materials and methods: Patients who underwent radical surgery for sporadic NF-PanNET G1 and G2 were retrospectively analysed. Linear regression analysis was performed to evaluate possible correlation between continuous variables. Multiple logistic regression and Cox’s regression analysis was performed.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Muffatti F

Authors: Muffatti F, Partelli S, Rancoita P, Andreasi V, Giannone F,

Keywords: NF-PanNET, tumor size, age, Ki-67,