Type 1 Gastric Neuroendocrine Tumor with SAPHO Syndrome Effectively Treated by Octreotide：A Case Report

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Introduction: Type 1 gastric neuroendocrine tumor (gNET) which is associated with chronic atrophic gastritis type A can be treated with SSA for the recurrence. SAPHO syndrome characterized by synovitis, acne, pustulosis, hyperostosis and osteitis is a kind of rare aseptic inflammation, which is thought to be related with abnormal autoimmune. Presently, there is no satisfied treatment for this illness.

Aim(s): To present a case with type 1 g-NET and SAPHO syndrome effectively treated with long-acting octreotide.

Materials and methods: A 54-year-old female with type 1 gNET who had recurrence disease after ESD therapy was treated with SSA for 22 months. Interestingly, the skin lesions of palmoplantar pustulosis and arthralgia before was disappeared during the treatment and was recurred after the treatment was terminate for 4 months. The diagnosis of palmoplantar pustulosis was confirmed by clinical manifestation and histopathological findings and hyperostosis and osteitis was confirmed by X-ray, so the diagnosis of SAPHO syndrome was made.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Dou D

Authors: Dou D, Wu Y, Tan H,

Keywords: gnet, SAPHO syndrome , SSA,