Value of Somatostatin Receptor Scintigraphy (SRS) in Patients with Appendiceal Neuroendocrine Neoplasms (ANEN) Based on Clinical Follow-up and Results of NETest

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Introduction: Neuroendocrine neoplasms of the appendix (ANEN) are one of the most commonly identified gastroentropancreatic tumours (GEP). The aim of this retrospective study was to review the value of Somatostatin Receptor Scintigraphy (SRS) in staging and imaging follow-up of patients with confirmed ANEN, NENG1 and NENG2 in single institution.

Aim(s): The aim was to compare results of SRS to a new approach using PCR-based test of specific circulating neuroendocrine tumour transcripts (NETest) to exclude presence of active disease.

Materials and methods: Overall, 90 patients with confirmed ANEN. Whole body (WB) and SPECT/CT SRS using 99mTc HYNICTOC was performed to assess disease extent before/after additional surgery and imaging follow-up. NETest were measured in selected 22 subjects.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Konsek S, Kolasińska-Ćwikła A, Lewczuk-Myślińska A, Kidd M, Buscombe J,

Keywords: appendiceal neuroendocrine neoplasm, ANEN, somatostatin receptor scintigraphy, SRS, NETest,