Introduction: Goblet cell carcinoma of the appendix is a rare tumor that can be classified as a subtype of mixed adeno-neuroendocrine carcinomas.
Aim(s): A 61 year old Caucasian male that presented with symptomatology of subocclusive syndrome was intraoperatively diagnosed with a stenotic ileal tumor with the involvement of the appendix.
Materials and methods: The resected specimens displayed an ileal and appendix tumoral proliferation with signet ring cell in a concentric pattern and perineural invasion. The immunohistochemical stain was positive for Chromogranin A, Synaptophysin and SSTR5, negative for SSTR2 and with 3-5% nuclear reactivity for Ki67%, suggestive for a goblet cell carcinoma of the appendix-G2 pT4bNxR1. A second tumor debulking was performed after 3 months, which revealed residual ileal and appendix tumors with hystopathological findings of mucinous adenocarcinoma invading the omentum.
Conference: 13th Annual ENETS conference 2016 (2016)
Category: ...none of the above
Presenting Author: MD Ioana Maria Lambrescu
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