Vipomas: Report of Three Cases in Ten Years

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Introduction: VIPoma is a rare neuroendocrine tumor (NET) with an incidence of one in 10 million per year. Most cases arise within the pancreas, with others reported in the lungs, colon, liver, adrenals, and neuroganglia.

Aim(s): We report three cases of VIPomas (two pancreatic and a jejunal one) observed in our Center in a period of 10 years.

Materials and methods: From January 2000 to December 2009, three cases (M:F 2:1; mean age 67.7 yrs) of VIPomas were observed in our Center (out of 164 Gastroenteropancreatic tumors). All patients were symptomatic (watery diarrhea) and with a high serum VIP. In one patient, a jejunal resection and hepatic metastasectomy were performed. In the second patient, a distal pancreatectomy and hepatic metastasectomy were performed. Both patients had a SST-analogue treatment after surgery. The last patient had a pancreatic head lesion; she underwent a pylorus-preserving pancreaticoduodenectomy.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Moletta L, Milanetto A, Liço V, De Carlo E, Alaggio R,

Keywords: vipoma, neuroendocrine tumors, pancreatic resections,