Abstract Library
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ENETS Abstract Search
Introduction: Several Phase-II trials have been designed to evaluate Tyrosine Kinase Inhibitor (TKI) and in particular Pazopanib in Neuroendocrine Neoplasia (NEN) but it’s efficacy is not yet demonstrated in a randomized Phase III trial.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Bongiovanni A, Liverani C, Recine f, Fausti V, Mercatali L,
Keywords: pazopanib, neuroendocrine neoplasia, neuroendocrine tumors, meta-analysis, carcinoid,
Introduction: The negative notch regulator DLL3 has gained increasing attention in tumors with neuroendocrine features, in particular SCLC, LCNEC and neuroendocrine prostate cancer, both as prognostic marker and candidate therapeutic target. No data are available on the expression of DLL3 in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs).
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Liverani C
Authors: Liverani C, Bongiovanni A, Pieri F, Foca F, Ravaioli S,
Keywords: DLL3, RB1, prognostic biomarker, GEP-NEN,
Introduction: Su has shown PFS improvement in patients (pt) with PNET in phase III trial
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Marconcini R
Authors: Marconcini R, Bloise F, Pusceddu S, Femia D, Bongiovanni A,
Keywords: sunitinib,
Introduction: Gastroenteropancreatic neuroendocrine neoplasia (GEP-NENs) are divided on the basis of Ki67 status into G1-G2 neuroendocrine tumors (NETs) (Ki67 <20%) and neuroendocrine carcinoma (NECs) (Ki67 >20% ). NEC patients generally have a poor prognosis and the first choice treatment is chemotherapy.A cisplatin/etoposide combination is often used as NECs are considered clinically similar to small cell lung cancer (SCLC), but no literature data is available. There is some evidence to suggest that carboplatin may also be effective in metastatic SCLC.
Conference: 12th Annual ENETSConcerence (2015)
Presenting Author: IBRAHIM T
Authors: Bongiovanni A, Riva N, Monti M, Ianniello A, Pieri F,
Keywords: GEP-NEC,chemotherapy,