A Better Ki-67 Index Cutoff to Redefine Low Grade NET and High Grade NEC in Grade 3 Gastroenteropancreatic Neuroendocrine Neoplasms

#1693

Introduction: Heterogeneity of Grade 3 (G3) gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) was reported and well-differentiated G3 NET (neuroendocrine tumor) was classified by previous studies.

Aim(s): To evaluate the role of Ki-67 index in the heterogeneity assessment of G3 patients and to identify prognostic factors for G3 patients.

Materials and methods: Clinical data of 223 patients with G3 GEP-NENs presenting to the Wuhan Union Hospital and the First Affiliated Hospital of Sun Yat-Sen University from 2009 to 2015 was analyzed.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Shi H

Authors: Shi H, Chen L, Zhang Q, Han C, Ding Z,

Keywords: gastroenteropancreatic neuroendocrine neoplasms, Ki67 index, prognostic factors,