Action of the Hypothalamic Proline-Rich Peptide During Vestibular Compensation Following Unilateral Labyrinthectomy Abstract #799

Introduction: There are uncovered mechanisms of the vestibular compensation (VC), following unilateral labyrinthectomy (UL). We consider the hypothalamic proline-rich peptide (PRP-1) action on Deiters’ lateral vestibular nucleus (LVN) neurons upon dynamics of recovery after UL was carried out.
Aim(s): Early and late tetanic, post-tetanic potentiation and depression of neurons to bilateral high frequency stimulation of hypothalamic supraoptic and paraventricualar nuclei was studied. The analysis of spike activity by on-line selection and software package was produced.
Materials and methods: The complex averaged peri event time and frequency histograms were constructed. The increase of inhibitory and excitatory reactions of Deiters’ neurons at early stage of VC following PRP-1 injection reaching the norm at late stage was revealed. Moreover, the shifts of post-stimulus activation are relatively more expressive when high frequency stimulation by 100Hz.
Conference: 11th Annual ENETS Conference (2014)
Category: Surgical treatment
Presenting Author: Research Fellow Lilia Hambardzumyan

To read results and conclusion, please login ...

Further abstracts you may be interested in

#790 Cerebellar and hypothalamic regulation of vestibular compensation after unilateral labyrinthectomy in rat
Introduction: The mechanisms of inhibitory regulation of neuronal activity of the vestibular system in health and in the vestibular compensation (VC) occurred with participation of the cerebellum, while non-cerebellar pathways are essential in restoring the stability of visual orientation during movement.
Conference: 11th Annual ENETS Conference (2014)
Category: Basic Science - In vitro models, tumor growth, CTCs
Presenting Author: MS, PhD Larisa Manukyan
Authors: Manukyan L
#798 Neuroendocrine Functions and Labyrinthectomy
Introduction: We tested the action of proline-rich peptide (PRP-1) and cobra venom Naja Naja Oxiana (NOX) on Deiters' nucleus neurons at 3rd, 15th and 35th days after unilateral labyrinthectomy (UL). Early and late tetanic, post-tetanic potentiation and depression of Deiters' neurons to bilateral high frequency stimulation of hypothalamic supraoptic and paraventricualar nuclei was studied. The analysis of spike activity was carried out by mean of on-line selection and special program.
Conference: 11th Annual ENETS Conference (2014)
Category: Basic Science - In vitro models, tumor growth, CTCs
Presenting Author: Lilit Darbinyan
Authors: Darbinyan L
#731 Gastroenteropancreatic (GEP) Neuroendocrine Tumors, Epidemiology and Clinical Retrospective Study from a Tertiary Care Center in North India
Introduction: Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasm derived from peptide- and amine-producing cells of the neuroendocrine system, characterized by the intracellular presence of markers of endocrine tissue, like chromogranin A, synaptophysin, neuronspecific enolase and having low to medium malignant potential.
Conference: 10th Annual ENETS Conference (2013)
Category: Epidemiology/Natural history/Prognosis - Registries, nationwide and regional surveys
Presenting Author: Dr Dipanjan Panda
#13 Neoadjuvant peptide receptor radionuclide therapy for an inoperable neuroendocrine pancreatic carcinoma
Introduction: Pancreatic endocrine tumors (pNETs) are rare but are among the most common neuroendocrine neoplasms of the abdomen. At diagnosis, many of them are already advanced and difficult to treat.
Conference: 7th Annual ENETS Conference (2010)
Category: Clinical
Presenting Author: Dr. Daniel Kaemmerer
#67 Interest of combined chromogranin A and pancreatic polypeptide for diagnosis and follow-up of gastroenteropancreatic endocrine carcinoma
Introduction: Assessment of tumor burden changes is essential for the management of well-differentiated gastroenteropancreatic neuroendocrine carcinoma (GEPNET). Chromogranin A (CgA) is the principal tumor marker for such tumors; however, its use to evaluate morphological tumor progression is not validated. Combined CgA and pancreatic polypeptide (PP) may increase sensitivity in the diagnosis of GEP-NET.
Conference: 7th Annual ENETS Conference (2010)
Category: Basic
Presenting Author: Dr Thomas WALTER
Close
Notice
Important Notice:

In preparation of the upcoming ENETS Barcelona 2018 Annual Conference, we have discovered in the world wide web at least one professional entity suggestive of possessing an ENETS mandate for conference registrations. Therefore, we must inform you that 100% of all conference participants are registered through ENETS official website www.enets.org and http://enetsconference.org/. There are no further options to validly register for Barcelona 2018 (or for any other ENETS event).

Please stay away from fraudulent scams abusing the ENETS acronym to register – and charge you above official ENETS conference fees! Such entities, against whom ENETS presses criminal charges, are neither authorized, nor commissioned nor instructed by ENETS to make such representations.