Biochemical Markers in Diagnosis and Monitoring of Neuroendocrine Tumors

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Introduction: The biochemical diagnosis and monitoring of neuroendocrine tumors is very important in the clinical management of patients.

Aim(s): To evaluate the utility of biochemical markers chromogranin A (CgA) and 5-hydroxyindoleacetic acid (5-HIAA) in diagnosis and monitoring of patients with neuroendocrine tumors (NETs).

Materials and methods: Biochemical markers were studied in 73 patients with pathologically proven gastroenteropancreatic (n=63) and bronchial (n=10) NETs. Plasma level of CgA was measured using Chromogranin A ELISA Kit (Dako), for the determination of urinary 5-HIAA a 5-HIAA ELISA (IBL International) kit was used.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Lyubimova N, Kostyleva O, Markovich A,

Keywords: neuroendocrine tumor, biochemical markers, diagnosis, monitoring,